Nearly 10 million people live in the Louisville, Indianapolis, Cincinnati, Dayton and Columbus region. Over $150 billion is spent on health care annually across their states. Each city is also home to at least two major health systems, a children’s hospital and at least one medical school. Notable organizations include:

Humana – a large, diversified payor – Louisville, Kentucky

UPS Supply Chain Solutions – a major logistics hub for pharmaceuticals, biologics and medical equipment repair – Louisville, Kentucky

Cincinnati Children’s Hospital – a top 5 children’s institution – Cincinnati, Ohio

Medpace – a publicly-traded clinical research organization – Cincinnati, Ohio

CareSource – a rapidly growing payor – Dayton, Ohio

Air Force Research Lab, Human Performance Wing – Dayton, Ohio

Cardinal Health – one of the world’s largest pharmaceutical and medical supply companies – Columbus, Ohio

Elevance (fka Anthem) – a large, diversified payor – Indianapolis, Indiana

Lilly Pharmaceuticals – an iconic brand in life sciences – Indianapolis, Indiana

Companies of note in the broader region include HCA in Nashville, Centene in St. Louis and UnitedHealth Group in Minneapolis.

Each city boasts a number of innovative companies across the healthcare and life sciences segments:

Bamboo Health, Sentry Health, Pharmacord and Waystar – Louisville, Kentucky

PatientPoint, Health Carousel, IncludeHealth and CTI Clinical Trials – Cincinnati, Ohio

Quartet RX / P&C Pharma and Ischemia Care – Dayton, Ohio

AndHealth, Beam Benefits, Olive and Quantum Health – Columbus, Ohio

INCOG Biopharma, Springbuk and Trimedx – Indianapolis, Indiana